To summarize the clinical nursing experience of 3 children with high flow fistula of digestive tract who underwent gastric fluid,bile fluid and intestinal fluid reinfusion combined with relay-type nutritional support. The key points of nursing include：nutritional risk screening and assessment,implementation of relay nutritional support treatment,enteral nutrition combined with digestive fluid reinfusion,fistula management and humanistic care for children and their parents. After careful treatment and nursing care,the weight of the 3 children increased steadily and their nutritional status improved gradually. All of them recovered and were discharged from hospital smoothly.